Myokinase Equilibrium

Initial velocity and equilibrium kinetics of myokinase.

The mechanism of myokinase (ATP-AMP phosphotransferase, EC 2.7.4.3) from rabbit muscle has been investigated by studies of equilibrium isotope exchange and initial velocities. The mechanism for the myokinase reaction is random bi bi. Under most conditions, equilibrium isotope exchange between AMP and ADP is faster than that between ATP and ADP. The rate-limiting steps in the reaction include th...

Myokinase activity of coronary arteries.

In exploring the mechanism of action of vasodilating drugs an attempt has been made to study the enzyme systems of the blood vessels. A transphosphatase of the myokinase type has been found to be present in the coronary arteries of the steer. The activity has been studied under the optimal conditions for this enzyme system. Coronary arterial tissue may be maintained at the temperature of dry ic...

Kinetic studies on rabbitmuscle myokinase.

The purification and properties of rabbit-muscle myokinase.

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The Role of Myokinase in Transphosphorylations* I. the Enzymatic Phosphorylation of Hexoses by Adenyl

The enzyme which catalyzes the phosphorylation of glucose and fructose was described in 1927 by Meyerhof (1). He found that muscle extracts which split polysaccharides and hexose phosphates to lactic acid but were unable to ferment hexoses could be enabled to ferment glucose and fructose by addition of a protein fraction from bakers’ yeast. The same protein fraction activated the aerobic oxidat...